Analysis of the osteoclast methylome for characterisation of epigenetic mechanisms underlying metabolic bone disease [ 1/1/2021 - 12/31/2022 ]

Research Grant

Brief description A large number of genetic variants have been identified that have a role in osteoporosis, however for many of these, the mechanism by which they influence the disease remains to be determined. This study will fill a critical knowledge gap by investigating the epigenetic control of gene expression in osteoclasts (bone resorbing cells). This research will generate a unique international resource that will provide foundation data to understand and treat this prevalent and debilitating bone disease.

Funding Amount $299,018

Funding Scheme Ideas Grants

Chief Investigator Dr Benjamin Mullin

Notes Ideas Grants