Analysis of human CD4+ T-cell responses to epitopes formed by peptide fusion in the pathogenesis of type 1 diabetes [ 2017 - ]

Research Grant

Researchers: Dr Stuart Mannering (Principal investigator) ,  Dr Hugh Reid ,  Prof Kathryn Haskins

Brief description Type 1 diabetes is caused by immune-mediated destruction of the insulin-secreting beta cells. Recently we discovered new targets ‘seen’ by the immune system that may explain why the immune system causes type 1 diabetes. Here we will determine if responses to these targets cause type 1 diabetes. This is important because it tests a new idea and our results will have a major impact on efforts to develop new therapies for type 1 diabetes an other autoimmune diseases.

Funding Amount $1,239,989.00

Funding Scheme Project Grants

Notes Standard Project Grant