Analysis of circulating tumour DNA for mutational characterisation and tracking disease progression in multiple myeloma [ 2018 - 2021 ]

Research Grant

Researchers: Prof Andrew Spencer (Principal investigator) ,  Dr Sridurga Mithraprabhu

Brief description Multiple myeloma is cancer of plasma cells in the bone marrow and presents at multiple sites with dissimilar genetic information (GI) across these sites. Invasive biopsies of multiple sites are required to determine the GI. Cancer cells shed small amounts of DNA into the blood stream and this circulating DNA (ctDNA) contains GI from multiple cancer sites. This project will evaluate the utility of ctDNA to determine GI and to predict treatment response in MM patients.

Funding Amount $AUD 921,397.66

Funding Scheme Project Grants

Notes Standard Project Grant