Why is there an increased risk of severe adverse perinatal outcomes after the use of clomiphene citrate for infertility treatment? [ 2018 - 2020 ]

Research Grant

Researchers: Prof Michael Davies (Principal investigator) ,  A/Pr Darryl Russell ,  A/Pr Lynne Giles ,  A/Pr Michael Stark ,  Dr Alice Rumbold
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Brief description Clomiphene citrate (CC) has been a first line treatment for female infertility internationally since the 1960’s. However, safety studies using routine prescribing practices were never performed, and numerous data sources now indicate that CC is associated with major adverse outcomes if the fetus is inadvertently exposed. We are linking prescription data to perinatal outcomes to confirm how CC is associated with adverse events so as to inform prescriber and practice change.

Funding Amount $AUD 570,064.97

Funding Scheme Project Grants

Notes Standard Project Grant