grant

An essential role for skeletal muscle FoxO1 in protecting against obesity-induced insulin resistance [ 2011 - 2013 ]

Also known as: Activation of a transcription factor to prevent obesity and insulin resistance

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1007465]

Researchers: Prof Mark Febbraio (Principal investigator)

Brief description Skeletal muscle is the largest organ in the human body and accounts for approximately 80% of glucose disposal after a meal. We have identified a transcription factor, namely FoxO1, that appears protect against obesity-induced insulin resistance by promoting energy consumption. This project will examine whether skeletal muscle specific activation of FoxO1 is a possible therapeutic target for the treatment of obesity-induced insulin resistance.

Funding Amount $AUD 593,888.23

Funding Scheme Project Grants

Notes Standard Project Grant

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