An Australasian, multi-centre, randomized, double-blind, placebo-controlled trial of the efficacy of fluoxetine in improving functional recovery after acute stroke [ 2014 - 2018 ]

Research Grant

Researchers: Prof Graeme Hankey (Principal investigator) ,  A/Pr Christopher Etherton-Beer ,  A/Pr Laurent Billot ,  A/Pr Maree Hackett ,  Dr Andrew Ford
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Brief description Stroke is one of the top three causes of disability. Treatments that improve recovery after stroke are lacking. We reviewed the world literature and found a number of very small studies which, together, suggest that the antidepressant drug, fluoxetine, may improve the recovery in stroke patients. AFFINITY is a large trial in 1600 Australians and New Zealanders with stroke which aims to find out whether taking fluoxetine for 6 months after a stroke improves recovery compared to a placebo.

Funding Amount $AUD 2,306,367.21

Funding Scheme Project Grants

Notes Standard Project Grant