An apotope of Ro60 in lupus [ 2010 - 2012 ]

Research Grant

Researchers: Prof Thomas Gordon (Principal investigator) ,  Prof David Gordon

Brief description This project introduces a new biomarker in systemic lupus erythematosus termed an apotope. The aims are to study the diagnostic potential of an apotope of Ro60, a key target in lupus, together with its ability to initiate the disease and cause organ damage. The interaction of the Ro60 apotope with a novel protective factor called beta2-glycoprotein I will also be studied. These discoveries are likely to lead to new diagnostic tests and preventions for lupus and neonatal lupus.

Funding Amount $AUD 539,773.79

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant