grant

An Achilles’ heel of ovarian cancer: targeting ARID1A mutant tumours

Also known as: Ideas Grants

Funded by National Health and Medical Research Council
Managed by University of Technology Sydney
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/2019296]

Funding Amount $1,199,273.00

Full description Five-year survival for most women with ovarian cancer is poor, with drug resistance a major problem, especially once relapsed. Outcomes are particularly dismal for the sub-type ovarian clear cell carcinoma that is particularly drug resistant. We are looking beyond the DNA to the “epigenome” to target factors involved in changing the landscape of DNA in order to identify new therapies to treat ovarian cancer, overcome chemoresistance and extend the lives of women with this malignancy.

Chief Investigator Prof Deborah Marsh

Date Announced 2022-12-14T00:00:00

Sector University

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Spatial Coverage And Location

text: NSW

Subjects
Basic Science Research | Cancer Cell Biology | Cancer Therapy (Excl. Chemotherapy and Radiation Therapy) | Medical and Health Sciences | Molecular Targets | Oncology and Carcinogenesis | biomedical and clinical sciences | cancer biology | cancer cell biology | gynaecological cancers | molecular biology | ovarian cancer |
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