Data

Amplimune

Commonwealth Scientific and Industrial Research Organisation
Alexander, Annika ; Ingham, Aaron ; Colditz, Ian ; Hine, Brad ; Doyle, Emma ; Almeida Alexandre, Pamela
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.25919/hty2-hj21&rft.title=Amplimune&rft.identifier=https://doi.org/10.25919/hty2-hj21&rft.publisher=Commonwealth Scientific and Industrial Research Organisation&rft.description=This collection of data is from four experimental trials investigating the effect of the immune stimulant Amplimune® (NovaVive Inc., Napanee, Ontario, Canada) on immune and physiological responses in Australian beef cattle. The aim was to explore the potential of the immune stimulant to enhance immune responses and protect cattle against a range of pathogens.Lineage: Immune and physiological responses were measured following administration of Amplimune to cattle in vivo (live animal), or cattle immune cells in vitro (in the laboratory). Immune responses were measured using a haematological analyser, enzyme-linked immunosorbent assays, cell culture and RNA extraction, PCR and sequencing. Physiological responses were measured using temperature loggers, weight scales and physical assessment (by a veterinarian). These data (except the sequencing data) were all stored in excel spreadsheets. The sequencing data was stored as zipped fastq files.&rft.creator=Alexander, Annika &rft.creator=Ingham, Aaron &rft.creator=Colditz, Ian &rft.creator=Hine, Brad &rft.creator=Doyle, Emma &rft.creator=Almeida Alexandre, Pamela &rft.date=2023&rft.edition=v1&rft.coverage=151.5608,-30.5869&rft_rights=Creative Commons Attribution 4.0 International Licence https://creativecommons.org/licenses/by/4.0/&rft_rights=Access to the data is restricted&rft_rights=All Rights (including copyright) CSIRO 2023.&rft_subject=Amplimune&rft_subject=Cattle&rft_subject=Immune stimulants&rft_subject=Trained immunity&rft_subject=Bovine respiratory disease&rft_subject=Cytokines&rft_subject=Transcriptomics&rft_subject=Th1&rft_subject=Th17&rft_subject=Pro-inflammatory&rft_subject=Respiratory disease&rft_subject=Vaccines&rft_subject=Enhanced immunity&rft_subject=Genomics and transcriptomics&rft_subject=Bioinformatics and computational biology&rft_subject=BIOLOGICAL SCIENCES&rft_subject=Animal cell and molecular biology&rft_subject=Zoology&rft_subject=Animal immunology&rft_subject=Innate immunity&rft_subject=Immunology&rft_subject=BIOMEDICAL AND CLINICAL SCIENCES&rft.type=dataset&rft.language=English Access the data
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CC-BY

Creative Commons Attribution 4.0 International Licence
https://creativecommons.org/licenses/by/4.0/

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All Rights (including copyright) CSIRO 2023.

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This collection of data is from four experimental trials investigating the effect of the immune stimulant Amplimune® (NovaVive Inc., Napanee, Ontario, Canada) on immune and physiological responses in Australian beef cattle. The aim was to explore the potential of the immune stimulant to enhance immune responses and protect cattle against a range of pathogens.
Lineage: Immune and physiological responses were measured following administration of Amplimune to cattle in vivo (live animal), or cattle immune cells in vitro (in the laboratory). Immune responses were measured using a haematological analyser, enzyme-linked immunosorbent assays, cell culture and RNA extraction, PCR and sequencing. Physiological responses were measured using temperature loggers, weight scales and physical assessment (by a veterinarian). These data (except the sequencing data) were all stored in excel spreadsheets. The sequencing data was stored as zipped fastq files.

Available: 2023-06-16

Data time period: 2019-02-01 to 2022-12-31

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151.5608,-30.5869

151.5608,-30.5869

Subjects
Amplimune | Animal Cell and Molecular Biology | Animal Immunology | Biological Sciences | Biomedical and Clinical Sciences | Bioinformatics and Computational Biology | Bovine respiratory disease | Cattle | Cytokines | Enhanced immunity | Genomics and Transcriptomics | Immune stimulants | Immunology | Innate Immunity | Pro-inflammatory | Respiratory disease | Th1 | Th17 | Trained immunity | Transcriptomics | Vaccines | Zoology |

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Identifiers
ACN 633 798 857