grant

Alternate Splicing of tryptase genes regulates their specificity [ 2010 - 2014 ]

Also known as: Splice Variant Tryptases

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/630660]

Researchers: Dr John Hunt (Principal investigator) ,  Dr Katherine Bryant Prof H Patrick Mcneil

Brief description Tryptases are enzymes implicated in inflammatory disorders including arthritis, inflammatory bowel disease (IBD) and asthma. Specific tryptase inhibitors are effective in treating these diseases. We have discovered that each human tryptase gene is processed into two different protein products via a mechanism called alternate splicing. We will investigate the structure and function of these.

Funding Amount $AUD 294,250.22

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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