grant

The alpha5 GABA-A receptor: delineating an emerging therapeutic target [ 2017 - 2019 ]

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1120947]

Researchers: Prof Joseph Lynch (Principal investigator)

Brief description GABA-A receptors mediate inhibitory synaptic transmission in the brain. Receptors containing ?5 subunits are therapeutic targets for many neurological disorders. We aim to characterise the functional properties of the main ?5-containing isoforms using high-resolution imaging and whole-cell recording. Our goal is to understand which ?5-containing isoform should be preferentially targeted (and how) when seeking to treat the various disorders in which these receptors have been implicated.

Funding Amount $AUD 492,468.78

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857