The alpha5 GABA-A receptor: delineating an emerging therapeutic target [ 2017 - ]

Research Grant

Researchers: Prof Joseph Lynch (Principal investigator)

Brief description GABA-A receptors mediate inhibitory synaptic transmission in the brain. Receptors containing α5 subunits are therapeutic targets for many neurological disorders. We aim to characterise the functional properties of the main α5-containing isoforms using high-resolution imaging and whole-cell recording. Our goal is to understand which α5-containing isoform should be preferentially targeted (and how) when seeking to treat the various disorders in which these receptors have been implicated.

Funding Amount $481,178.00

Funding Scheme Project Grants

Notes Standard Project Grant