grant

Airway extracellular matrix and smooth muscle in chronic obstructive pulmonary disease (COPD) [ 2014 - 2018 ]

Also known as: Airway extracellular matrix and smooth muscle in COPD

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1063068]

Researchers: Prof Alan James (Principal investigator) ,  Prof Gregory King Dr Peter Mcfawn Dr Brent Mcparland Dr Peter Noble

Brief description In asthma the layer of airway smooth muscle is thicker, due to more muscle cells. Airway narrowing is excessive but reversible. In chronic obstructive pulmonary disease (due mainly to smoking) the layer of airway smooth muscle is also thicker but the airways cannot be induced to open, or close. Our data suggest that this fixed airway narrowing is likely to be due to an excess of matrix between cells rather than muscle. This project will comprehensively test this new finding.

Funding Amount $AUD 828,849.81

Funding Scheme Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]