Adenosine Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease [ 2018 - ]

Research Grant

Researchers: Dr Lauren May (Principal investigator) ,  A/Pr Paul White ,  Dr Andrew Kompa

Brief description Heart attacks and secondary heart failure remain significant health burdens. Stimulation of adenosine receptors located on heart cells confers powerful cardiac protection, improving acute and longer-term heart function subsequent to a heart attack but avoiding the usual unwanted effects from this approach. We aim to better understand the mechanism of action of potential adenosine receptor therapeutics and establish the clinical potential of these compounds using animal models of heart failure.

Funding Amount $1,007,638.00

Funding Scheme Project Grants

Notes Standard Project Grant