Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions [ 2018 - ]

Research Grant

Researchers: Prof Arthur Christopoulos (Principal investigator) ,  Dr Daniel Scott ,  Dr Lauren May ,  Dr Wendy Imlach ,  Prof Stephen Hill

Brief description This project will investigate the properties of an important family of proteins that play a major role in diseases such as chronic pain and cardiovascular illnesses. It will apply multidisciplinary, cutting-edge, approaches to understand how different types of drugs act on these proteins, and use this information to develop novel drug leads that can modulate these proteins in a more selective and efficacious manner, with a particular emphasis on targeting chronic pain conditions.

Funding Amount $1,788,960.00

Funding Scheme Project Grants

Notes Standard Project Grant