Additional file 3 of Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

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Additional file 3: Supplementary Table S8, Supplementary Table S9, Supplementary Table S10, Supplementary Table S11, and Supplementary Table S12. Supplementary Table S8. Shows the BFDPs under two more restrictive prior probabilities of true association (10-5 and 10-6) for the results presented in Table 1. Supplementary Table S9. Shows the BFDPs under two more restrictive prior probabilities of true association (10-5 and 10-6) for the results presented in Table 2. Supplementary Table S10. Shows power calculation by subgroup, at the two-sided 5E-08 level for varying genotype hazard ratio (GHR) and minor allele frequency (MAF), based on number of cases and event rate from the 15-year breast cancer-specific analyses. Supplementary Table S11. Shows power calculation by subgroup, at the two-sided 5E-08 level for varying genotype hazard ratio (GHR) and minor allele frequency (MAF), based on number of cases and event rate from the 5-year breast cancer-specific analyses. Supplementary Table S12. Shows the subgroup-specific associations detected by previous studies and corresponding estimates from the current study.

Notes

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Antoni van Leeuwenhoek Hospital; Queensland Institute of Medical Research; National Cancer Institute; Lunenfeld-Tanenbaum Research Institute; University of California Berkeley; German Cancer Research Center; Fred Hutchinson Cancer Center; Lund University; University Medical Center Hamburg-Eppendorf; University Hospital Erlangen; University of Cambridge; Ruhr University Bochum; University of Utah; Kaiser Permanente; Roswell Park Cancer Institute; University of Sydney; Mayo Clinic Phoenix; University of Sheffield; Karolinska Institutet; Fox Chase Cancer Center; Hannover Medical School; International Agency for Research on Cancer; University of Westminster; University of Southampton; Harvard University; University of Manchester; University of Copenhagen; Curtin University; University Hospital San Carlos - Hospital Clinico San Carlos; University of Melbourne; University of Oulu; Institut national de la santé et de la recherche médicale; University of Cologne; University of Southern California; University of Eastern Finland; Erasmus MC; University of Tübingen; University of Oxford; Pomeranian Medical University in Szczecin; University Hospital Ulm; Stanford University; KULeuven BIOTEC; Oslo University Hospital; City of Hope; University of Hawai'i at Mānoa; Heraklion University Hospital; Monash University; University of Toronto; University of Helsinki; University of North Carolina at Chapel Hill; Queen's University Belfast; American Cancer Society; Fondazione IRCCS Istituto Nazionale dei Tumori; FIRC Institute of Molecular Oncology; Carmel Medical Center; Puerta de Hierro Majadahonda University Hospital; University College London; University Hospital of Larissa; King's College London; Heidelberg University ; Saints Cyril and Methodius University of Skopje; Institute of Cancer Research; Cornell University; Columbia University; Leiden University; Centre NordLab; Uppsala University; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology

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