Data

Additional file 1 of Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium

The University of Western Australia
Neumann, Alexander ; Sammallahti, Sara ; Cosin-Tomas, Marta ; Reese, Sarah E. ; Suderman, Matthew ; Alemany, Silvia ; Almqvist, Catarina ; Andrusaityte, Sandra ; Arshad, Syed H. ; Bakermans-Kranenburg, Marian J. ; Beilin, Lawrence ; Breton, Carrie ; Bustamante, Mariona ; Czamara, Darina ; Dabelea, Dana ; Eng, Celeste ; Eskenazi, Brenda ; Fuemmeler, Bernard F. ; Gilliland, Frank D. ; Grazuleviciene, Regina ; Håberg, Siri E. ; Herberth, Gunda ; Holland, Nina ; Hough, Amy ; Hu, Donglei ; Huen, Karen ; Hüls, Anke ; Jarvelin, Marjo-Riitta ; Jin, Jianping ; Julvez, Jordi ; Koletzko, Berthold V. ; Koppelman, Gerard H. ; Kull, Inger ; Lu, Xueling ; Maitre, Léa ; Mason, Dan ; Melén, Erik ; Merid, Simon K. ; Molloy, Peter L. ; Mori, Trevor A. ; Mulder, Rosa H. ; Page, Christian M. ; Richmond, Rebecca C. ; Röder, Stefan ; Ross, Jason P. ; Schellhas, Laura ; Sebert, Sylvain ; Sheppard, Dean ; Snieder, Harold ; Starling, Anne P. ; Stein, Dan J. ; Tindula, Gwen ; van IJzendoorn, Marinus H. ; Vonk, Judith ; Walton, Esther ; Witonsky, Jonathan ; Xu, Cheng-Jian ; Yang, Ivana V. ; Yousefi, Paul D. ; Zar, Heather J. ; Zenclussen, Ana C. ; Zhang, Hongmei ; Tiemeier, Henning ; London, Stephanie J. ; Felix, Janine F. ; Cecil, Charlotte
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.6084/m9.figshare.28792901&rft.title=Additional file 1 of Epigenetic timing effects on child developmental outcomes: a longitudinal meta-regression of findings from the Pregnancy And Childhood Epigenetics Consortium&rft.identifier=10.6084/m9.figshare.28792901&rft.publisher=Figshare&rft.description=Additional file 1. Table S1: Cohort sample sizes. Table S2: Number of cohorts overlapping. Table S3a: Absolute effect size percentiles. Table S3b: Number of DNAm sites with nominally significant change per effect direction pattern. Table S4: Association between DNA methylation either at birth or in childhood and child developmental outcomes. Table S5: Heterogeneity analyses. Table S6: Association between DNA methylation either at birth or in childhood and child developmental outcomes. Table S7: Enrichment ADHD. Table S8: Enrichment GPF. Table S9: Enrichment Sleep. Table S10: Enrichment BMI. Table S11: Enrichment Asthma&rft.creator=Neumann, Alexander &rft.creator=Sammallahti, Sara &rft.creator=Cosin-Tomas, Marta &rft.creator=Reese, Sarah E. &rft.creator=Suderman, Matthew &rft.creator=Alemany, Silvia &rft.creator=Almqvist, Catarina &rft.creator=Andrusaityte, Sandra &rft.creator=Arshad, Syed H. &rft.creator=Bakermans-Kranenburg, Marian J. &rft.creator=Beilin, Lawrence &rft.creator=Breton, Carrie &rft.creator=Bustamante, Mariona &rft.creator=Czamara, Darina &rft.creator=Dabelea, Dana &rft.creator=Eng, Celeste &rft.creator=Eskenazi, Brenda &rft.creator=Fuemmeler, Bernard F. &rft.creator=Gilliland, Frank D. &rft.creator=Grazuleviciene, Regina &rft.creator=Håberg, Siri E. &rft.creator=Herberth, Gunda &rft.creator=Holland, Nina &rft.creator=Hough, Amy &rft.creator=Hu, Donglei &rft.creator=Huen, Karen &rft.creator=Hüls, Anke &rft.creator=Jarvelin, Marjo-Riitta &rft.creator=Jin, Jianping &rft.creator=Julvez, Jordi &rft.creator=Koletzko, Berthold V. &rft.creator=Koppelman, Gerard H. &rft.creator=Kull, Inger &rft.creator=Lu, Xueling &rft.creator=Maitre, Léa &rft.creator=Mason, Dan &rft.creator=Melén, Erik &rft.creator=Merid, Simon K. &rft.creator=Molloy, Peter L. &rft.creator=Mori, Trevor A. &rft.creator=Mulder, Rosa H. &rft.creator=Page, Christian M. &rft.creator=Richmond, Rebecca C. &rft.creator=Röder, Stefan &rft.creator=Ross, Jason P. &rft.creator=Schellhas, Laura &rft.creator=Sebert, Sylvain &rft.creator=Sheppard, Dean &rft.creator=Snieder, Harold &rft.creator=Starling, Anne P. &rft.creator=Stein, Dan J. &rft.creator=Tindula, Gwen &rft.creator=van IJzendoorn, Marinus H. &rft.creator=Vonk, Judith &rft.creator=Walton, Esther &rft.creator=Witonsky, Jonathan &rft.creator=Xu, Cheng-Jian &rft.creator=Yang, Ivana V. &rft.creator=Yousefi, Paul D. &rft.creator=Zar, Heather J. &rft.creator=Zenclussen, Ana C. &rft.creator=Zhang, Hongmei &rft.creator=Tiemeier, Henning &rft.creator=London, Stephanie J. &rft.creator=Felix, Janine F. &rft.creator=Cecil, Charlotte &rft.date=2025&rft_subject=Medicine&rft_subject=Biotechnology&rft_subject=Neuroscience&rft_subject=FOS: Biological sciences&rft_subject=Molecular Biology&rft_subject=Genetics&rft_subject=Mental Health&rft_subject=Developmental Biology&rft_subject=Cell Biology&rft_subject=Cancer&rft.type=dataset&rft.language=English Access the data
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Additional file 1. Table S1: Cohort sample sizes. Table S2: Number of cohorts overlapping. Table S3a: Absolute effect size percentiles. Table S3b: Number of DNAm sites with nominally significant change per effect direction pattern. Table S4: Association between DNA methylation either at birth or in childhood and child developmental outcomes. Table S5: Heterogeneity analyses. Table S6: Association between DNA methylation either at birth or in childhood and child developmental outcomes. Table S7: Enrichment ADHD. Table S8: Enrichment GPF. Table S9: Enrichment Sleep. Table S10: Enrichment BMI. Table S11: Enrichment Asthma

Notes

External Organisations
Erasmus MC; University of Helsinki; Pompeu Fabra University; Westat; University of Bristol; Vall d'Hebron University Hospital; Karolinska Institutet; Vytautas Magnus University; University of Southampton; ISPA - Instituto Universitário; University of Southern California; Max Planck Institute of Psychiatry; University of Colorado Anschutz Medical Campus; University of California; Virginia Commonwealth University; Norwegian Institute of Public Health; Helmholtz-Zentrum für Umweltforschung; University of California Berkeley; Bradford Teaching Hospitals NHS Foundation Trust; Emory University; University of Oulu; Institut d’Investigació Sanitària Pere Virgili (IISPV); Ludwig Maximilian University of Munich; University of Groningen; Center for Biomedical Research in Epidemiology and Public Health; Commonwealth Scientific & Industrial Research Organisation; University of California San Francisco; University of North Carolina at Chapel Hill; University of Cape Town; Stanford University; Monash University; University of Bath; Hannover Medical School; University of Memphis; National Institute of Environmental Health Sciences; Leiden University
Associated Persons
Alexander Neumann (Creator); Sara Sammallahti (Creator); Marta Cosin-Tomas (Creator); Sarah E. Reese (Creator); Matthew Suderman (Creator); Silvia Alemany (Creator); Catarina Almqvist (Creator); Sandra Andrusaityte (Creator); Syed H. Arshad (Creator); Marian J. Bakermans-Kranenburg (Creator); Carrie Breton (Creator); Mariona Bustamante (Creator); Darina Czamara (Creator); Dana Dabelea (Creator); Celeste Eng (Creator); Brenda Eskenazi (Creator); Bernard F. Fuemmeler (Creator); Frank D. Gilliland (Creator); Regina Grazuleviciene (Creator); Siri E. Håberg (Creator); Gunda Herberth (Creator); Nina Holland (Creator); Amy Hough (Creator); Donglei Hu (Creator); Karen Huen (Creator); Anke Hüls (Creator); Marjo-Riitta Jarvelin (Creator); Jianping Jin (Creator); Jordi Julvez (Creator); Berthold V. Koletzko (Creator); Gerard H. Koppelman (Creator); Inger Kull (Creator); Xueling Lu (Creator); Léa Maitre (Creator); Dan Mason (Creator); Erik Melén (Creator); Simon K. Merid (Creator); Peter L. Molloy (Creator); Rosa H. Mulder (Creator); Christian M. Page (Creator); Rebecca C. Richmond (Creator); Stefan Röder (Creator); Jason P. Ross (Creator); Laura Schellhas (Creator); Sylvain Sebert (Creator); Dean Sheppard (Creator); Harold Snieder (Creator); Anne P. Starling (Creator); Dan J. Stein (Creator); Gwen Tindula (Creator); Marinus H. van IJzendoorn (Creator); Judith Vonk (Creator); Esther Walton (Creator); Jonathan Witonsky (Creator); Cheng-Jian Xu (Creator); Ivana V. Yang (Creator); Paul D. Yousefi (Creator); Heather J. Zar (Creator); Ana C. Zenclussen (Creator); Hongmei Zhang (Creator); Henning Tiemeier (Creator); Stephanie J. London (Creator); Janine F. Felix (Creator); Charlotte Cecil (Creator)

Issued: 2025-04-15

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Biotechnology | Cancer | Cell Biology | Developmental Biology | FOS: Biological sciences | Genetics | Medicine | Mental Health | Molecular Biology | Neuroscience |

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