Activin A and follistatin are potential key regulators of organ transplant dysfunction and graft survival. [ 2013 - 2015 ]

Research Grant

Researchers: Prof David De Kretser (Principal investigator) ,  A/Pr Mark Hedger ,  A/Pr Thomas Kotsimbos ,  Prof Greg Snell ,  Prof Karen Dwyer

Brief description The grant examines novel key regulators in organ transplantation. It examines molecules that are released during transplant surgery and on the return of blood flow to the organ which can cause inflammation and scarring. The release is increased by heparin, an anticoagulant used in organ preparation. Alternative anticoagulants and blockers of the regulators released will be tested to prevent the damage to the transplant, potentially improving both the short and long term graft survival and function.

Funding Amount $AUD 535,579.51

Funding Scheme Project Grants

Notes Standard Project Grant