Activation Transcription Factor-4: Novel Regulator of Smooth Muscle Cell Repair and Intimal Thickening through Tenascin C [ 2012 - 2013 ]

Research Grant

Researchers: Prof Levon Khachigian (Principal investigator)

Brief description CVD represents the most important cause of morbidity and mortality in the world, accounting for 35% of all deaths in Australia. Smooth muscle cell growth accounts for a range of vascular proliferative disorders. This project focuses on understanding the role of ATF-4 as a new key regulator of SMC proliferation and intimal thickening in injured vessels. Moreover, strategies targeting ATF-4 will facilitate future therapeutic strategies to control intimal thickening in patients with vascular disease.

Funding Amount $AUD 228,313.51

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant