Acquisition of long-term self-renewal by hematopoietic progenitors [ 2019 - ]

Research Grant

Brief description The KAT6A (MOZ monocytic leukemia zinc finger) protein causes cancer when it is mutated. We have shown that this protein is essential for maintaining blood stem cells. Blood stem cells are used in the clinic to treat blood cancers and immune disorders. In this project we will study how KAT6A controls the formation of stem cells and its role in blood cancers, with the long-term aim of improving stem cell and cancer therapies.

Funding Amount $823,212.00

Funding Scheme Project Grants

Notes Standard Project Grant