ABCA12 – a New Regulator of Cellular Lipid Metabolism and Inflammation [ 2012 - 2014 ]

Research Grant

Researchers: A/Pr Ian Smyth (Principal investigator) ,  Prof Dmitri Sviridov (Principal investigator) ,  A/Pr Jeremy Jowett ,  Dr Alan Remaley ,  Dr Ying Fu
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Brief description Dysregulation of cholesterol metabolism plays a key role in a number of diseases – from diabetes and atherosclerosis to neurological and skin disorders. Mechanisms of regulation of cholesterol metabolism are poorly understood. We have recently discovered a new pathway regulating cholesterol metabolism and in this study we will investigate molecular, cellular and physiological mechanisms of this pathway and will identify the possibilities to target it for therapeutic intervention.

Funding Amount $AUD 786,676.30

Funding Scheme Project Grants

Notes Standard Project Grant