ABCA1 _ an Intersection between Infection, Atherosclerosis and Metabolic Disorders [ 2012 - 2014 ]

Research Grant

Researchers: Prof Dmitri Sviridov (Principal investigator) ,  A/Pr Barry Slobedman ,  Dr Nigora Mukhamedova ,  Prof Michael Bukrinsky

Brief description Pathogens interfere with cellular cholesterol metabolism in order to support their lifecycle. Such interference may cause diseases not usually associated with infection, like cardiovascular disease. Restoring normal cholesterol metabolism may help treating infection and its metabolic consequences. We will investigate molecular, cellular and physiological mechanisms of interaction of pathogens with cholesterol metabolism to find a key point that can be targeted for therapeutic intervention.

Funding Amount $AUD 653,827.27

Funding Scheme Project Grants

Notes Standard Project Grant