Data

A randomised double-blind multi-site parallel arm controlled trial to assess relief of refractory breathlessness comparing fixed doses of morphine and placebo.

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Currow, David ; Palliative Care Clinical Studies Collaborative (PaCCSC) ; Palliative Care Clinical Studies Collaborative (PaCCSC)
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.58084/7VG4-QK30&rft.title=A randomised double-blind multi-site parallel arm controlled trial to assess relief of refractory breathlessness comparing fixed doses of morphine and placebo.&rft.identifier=http://doi.org/10.58084/7VG4-QK30&rft.publisher=Palliative Care Clinical Studies Collaborative (PaCCSC)&rft.description=Data set includes individual participant data for 299 consenting participants. A total of 284 participants were randomised (145 to Morphine, 139 to Placebo, and a further 74 participants to the oxycodone arm. The oxycodone arm was later dropped due to recruitment difficulties). The data sets includes CSV files for screening and baseline, day 1 and day 7 outcome data, and 4 weeks of follow-up. Data is available for clincial investigations, demographic information, Functional assessment (AKPS and DES), Dyspnoea descriptors, Breathlessness scores (VAS, Likert, and mMRC), EORTC QLQ-C15, and Respiratory Disease Questionnaire, Global Impression of Change, Carer Quality of Life, Life Space Assessment, Health Service Utilisation, Symptoms and Adverse Events.&rft.creator=Currow, David &rft.creator=Palliative Care Clinical Studies Collaborative (PaCCSC) &rft.creator=Palliative Care Clinical Studies Collaborative (PaCCSC) &rft.date=2024&rft.relation=https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=ACTRN12609000806268&rft_subject=Cardiovascular medicine and haematology (Respiratory diseases)&rft.type=dataset&rft.language=English Access the data
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Data set includes individual participant data for 299 consenting participants. A total of 284 participants were randomised (145 to Morphine, 139 to Placebo, and a further 74 participants to the oxycodone arm. The oxycodone arm was later dropped due to recruitment difficulties). The data sets includes CSV files for screening and baseline, day 1 and day 7 outcome data, and 4 weeks of follow-up. Data is available for clincial investigations, demographic information, Functional assessment (AKPS and DES), Dyspnoea descriptors, Breathlessness scores (VAS, Likert, and mMRC), EORTC QLQ-C15, and Respiratory Disease Questionnaire, Global Impression of Change, Carer Quality of Life, Life Space Assessment, Health Service Utilisation, Symptoms and Adverse Events.

Notes

HeSANDA 1.0.0

Issued: 2024

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Cardiovascular medicine and haematology (Respiratory diseases) |

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Other Information
Regular, sustained-release morphine for chronic breathlessness: a multicentre, double-blind, randomised, placebo-controlled trial

doi : https://doi.org/10.1136/thoraxjnl-2019-213681

Controlled-Release Oxycodone vs. Placebo in the Treatment of Chronic Breathlessness-A Multisite Randomized Placebo Controlled Trial

doi : http://doi.org/10.1016/j.jpainsymman.2019.10.017

Opioids for breathlessness: a narrative review

doi : https://doi.org/10.1136/bmjspcare-2020-002314

Australian Government

ROR : https://ror.org/0314h5y94

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