grant

A one-two punch therapeutic strategy to overcome chemotherapy-induced cell plasticity in neuroblastoma

Also known as: Ideas Grants

Funded by National Health and Medical Research Council
Managed by University of Technology Sydney
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/2029527]

Funding Amount $599,586.32

Full description Neuroblastoma is an aggressive child cancer. Treatments fail because minor cancer cell populations are naturally drug resistant due to their unique genetic makeup. We will use novel genetic sequencing of individual tumour cells to comprehensively detail the full spectrum of cancer cell types in neuroblastoma and how single cancer cells are evading anticancer drugs. With this, we aim to design customised therapeutic approaches targeted specifically against drug-resistant cells in the tumour.

Chief Investigator Assoc Prof Daniel Carter

Date Announced 2023-12-15T00:00:00

Sector University

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Spatial Coverage And Location

text: NSW

Subjects
Biological Sciences | Basic Science Research | Cancer Cell Biology | Cancer Therapy (Excl. Chemotherapy and Radiation Therapy) | Medical and Health Sciences | Oncology and Carcinogenesis | bioinformatics | bioinformatics and computational biology | biomedical and clinical sciences | cancer cell biology | drug resistance | genomics and transcriptomics | neuroblastoma | plasticity |
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