Feasibility Study of MSOC RCT 2021

The University of Melbourne

Dataset description

Demographic and health-related data were collected from 35 participants diagnosed with Multiple Sclerosis (MS) across Australia, Canada, New Zealand, and the United States as part of a feasibility study for a 6-week web-based educational lifestyle program (2021). Participants were aged 18 years or older and proficient in English. The dataset includes baseline and follow-up survey data on quality of life, disability, self-efficacy, fatigue, depression, and perceived social support. Additionally, it includes information on modifiable lifestyle factors such as diet, physical activity, sun exposure, vitamin D supplementation, stress reduction activities, alcohol intake, comorbidities, and medication use. Only participants who completed at least some modules of the course and provided complete baseline data are included.
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Source Study

Trial acronym

Not available

Trial ID





Not Applicable


Charities/Societies/Foundations,Overcoming Multiple Sclerosis Foundation

Scientific enquiries

Mr William Bevens

Brief Summary

The treatment of multiple sclerosis (MS) with immunomodulatory drugs play an important role for many people with MS (PwMS) in modifying disease progression. However, many come with significant side-effects. It has long been understood that lifestyle factors can impact the progression and outcome of MS, with programs targeting lifestyle components in PwMS describing improved quality-of-life (QoL) outcomes, disability, fatigue and mental health outcomes. The effectiveness of the Overcoming MS (OMS ....
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Key Inclusion Criteria

MS diagnosed by a physician. Lives in Australia, New Zealand, Canada, USA or UK. Internet connection.

Key Exclusion Criteria

Previously undertaken an Overcoming Multiple Sclerosis in-person course or engaged with any related material. Self-diagnosed MS (no physician diagnosis).

Can healthy volunteers participate?




Sample Size    35

Min. age    18 Years

Max. age    No limit

Sex    Both males and females

Condition category    multiple sclerosis

Condition code    Neurological


Intervention code Lifestyle , Treatment: Other

This is an online lifestyle education intervention. The course takes place modularly (6 modules) with key themes in each module: diet, physical activity, vitamin D and sunlight, stress, family incidence, final motivation. Each module contains narrated videos and animations, images with text, polls and quizzes. Modules are self-paced by participants, and participants can start and stop the modules at any time. Each module takes approximately 30 to 60 minutes to complete and will have access to al ....
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Control group Placebo

The control group is an identically structured online course with different content. The content is generic lifestyle content sourced from MS societies around the world. The goal is to replicate the generic information that many people with MS (PwMS) are exposed to through their healthcare. By including this in a parallel course as opposed to a wait-list control, the effectiveness of the course content rather than taking a course itself can be assessed.


Outcome: Feasibility, which is >40% of participants in the intervention arm, and >25% in the control arm complete 75% of the modules. These data will be measured by website analytics tool Hotjar, which provides data on traffic and engagement.
Timepoint: Feasibility end-point will be analysed at 8 weeks post-intervention commencement.

Data Dictionary: Not Available

Will individual participant data (IPD) for this trial be available?


What data in particular will be shared?

All IPD (after de-identification) collected during the study, not only what is published.

When will data be available?

Data will be made available as soon as publication of the primary findings is published. There is no proposed end date for when data will no longer be available.

Available to whom?

Any person with a valid reason to access the data, which will be at the discretion of the PI. This can include researchers but also members of the public, particularly those with MS and their families, who have an interest in this sort of research.

Available for what types of analyses?

Any purpose.

Source study information is derived from the Australian New Zealand Clinical Trials Registry (ANZCTR). For more information on the ANZCTR, please see