Monitoring Outcomes of Borderline personality disorder in Youth (MOBY).
ACTRN12610000100099
Treatment
Not Applicable
Government body,National Health and Medical Research
Prof Andrew Chanen
Borderline Personality Disorder (BPD) is a severe mental disorder that arises during adolescence and young adulthood. This study investigates the most effective form of early intervention for young people (15-25 years old) presenting for treatment of BPD for the first time. It is a randomised controlled trial comparing three interventions: two forms of the specialised HYPE early intervention (one with and one without 16 sessions of individual Cognitive Analytic Therapy), along with an interventi .... Read more
Broad inclusion criteria to capture the "real world" clincial environment. These are: (1) Age 15-25 inclusive, (2) Ability to give informed consent and comply with study procedures, (3) Fluency in English, (4) Structured Clinical Interview for DSM-IV axis II disorders BPD.
(1) First episode psychosis within the 12 months prior to entering the study, (2) Structured Clinical Interview for DSM-IV Axis 1 Bipolar I or II Disorder, (3) Psychiatric condition due to a medical condition, (4) Severe disturbance, such that the person is unable to comply with the requirements of informed consent or the protocol, (5) A Schizophrenia Spectrum Disorder, (6) prior evidence-based BPD treatment, (7) does not meet the clinical services' eligibility criteria (e.g. catchment area).
No
Sample Size 139
Min. age 15 Years
Max. age 25 Years
Sex Both males and females
Condition category Borderline personality disorder , Youth mental health
Condition code Mental Health
Intervention code Treatment: Other
Three interventions will be compared. Two of the interventions are two forms of the Helping Young People Early (HYPE) specialised early intervention for borderline personality disorder. The third intervention is youth mental health care. The three study arms will be: i) HYPE + individual Cognitive Analytic Therapy (HYPE+CAT); ii) HYPE + ‘Befriending’ (HYPE+Bef); iii) Youth mental health care + Befriending (YMH+Bef). HYPE+CAT is an integrated, multidisciplinary team-based early intervention servi .... Read more
Control group Active
YMH+Bef includes individual practice by specialist youth mental health clinicians within a government-funded multidisciplinary group practice setting. Clinicians carry a diagnostically mixed patient load. They diagnose mental disorders, develop a management plan, offer psychoeducation, conduct assertive case management and offer general psychiatric care. General practitioner and/or psychiatric referrals and pharmacotherapy are initiated as clinically indicated. Crisis and inpatient services are .... Read more
Outcome: Interpersonal problems measured by the Inventory of Interpersonal Problems Circumplex Version (IIP-C)Timepoint: Baseline, 3 months, 6 months, 12 months and 18 months.
Outcome: Social Adjustment measured by the Social Adjustment Scale Self Report (SAS-SR)Timepoint: Baseline, 3 months, 6 months, 12 months and 18 months.
yes
All of the individual trial-related participant data collected during the trial, after de-identification.
Immediately following publication and for an indefinite time.
Data will potentially be available to researchers from not-for profit organisations, commercial organisations or other based in any location. All data requests will be considered by the data custodian and the primary sponsor on a case-by-case basis. Requests must include a methodologically sound proposal. Specific conditions of use may apply and will be specified in a data sharing agreement (or similar) that the requester must agree to before access is granted. For further information, see Orygen data sharing policy.
Any type of analyses. Assessed on a case-by-case basis.