{"status":"OK","code":"200","message":{"message_version":"v1.0","api_version":"v2.0","format":"application\/json"},"data":{"numFound":72443,"offset":0,"limit":30,"records":[{"id":"1358613","key":"IMOS\/c2d47a05-2bb7-4649-ba05-d314e8f2105b","type":"program","title":"IMOS - Satellite Remote Sensing - Surface Waves Sub-Facility","description":"The Surface Waves Sub-Facility, part of the Satellite Remote Sensing Facility, will calibrate, collect and distribute ocean surface wave data from current and next-generation satellite missions.&lt;br\/&gt;&lt;br\/&gt;The Sub-Facility will build Australia\u2019s capability in Satellite Remotely Sensed wave data-streams and deliver global validated, processed wave data streams, with a focused effort in the Australian region. Activities will include:&lt;br\/&gt;&lt;br\/&gt;\u2022\tbuilding on the wave measurements obtained from the Bass Strait altimeter calibration sites for calibration of the current satellite missions in the Australian region,&lt;br\/&gt;\u2022\tusing the Southern Ocean Flux Station to validate wave data in the extreme Southern Ocean wave climate,&lt;br\/&gt;\u2022\tdelivering historical and near-real-time altimeter-derived significant wave heights to the IMOS OceanCurrent Facility, producing daily maps and animations that will be used by researchers and the broader community,&lt;br\/&gt;\u2022\tmanaging the delivery of wind-wave data derived from altimeter and synthetic aperture radar (SAR) satellite platforms to the Australian marine and coastal science community.","institutions":null,"researchers":null,"status":"other","fundingAmount":null,"fundingScheme":null,"startDate":null,"endDate":null,"dateTimeModified":"2025-07-02T19:51:06Z","dateTimeCreated":"2018-12-13T10:03:54Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":["c2d47a05-2bb7-4649-ba05-d314e8f2105b"],"subjects":["oceans","SIGNIFICANT WAVE HEIGHT","EARTH SCIENCE","OCEANS","OCEAN WAVES","SURFACE WINDS","OCEAN WINDS","SEA STATE","SWELLS","WIND WAVES","Surface Waves Sub-Facility, Integrated Marine Observing System (IMOS)","Global \/ Oceans | World"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/programs\/1358613"}]},{"id":"3012301","key":"IMOS\/8cdcdcad-399b-4bed-8cb2-29c486b6b124","type":"program","title":"IMOS - National Reef Monitoring Network Sub-Facility","description":"The National Reef Monitoring Network brings together shallow reef surveys conducted around Australia into a centralised database. The IMOS National Reef Monitoring Network sub-Facility collates, cleans, stores and makes this data rapidly available from contributors including: Reef Life Survey, Parks Australia, Department of Biodiversity, Conservation and Attractions (Western Australia), Department of Environment, Water and Natural Resources (South Australia), Department of Primary Industries (New South Wales), Tasmanian Parks and Wildlife Service and Parks Victoria.&lt;br\/&gt;&lt;br\/&gt;The data provided by the National Reef Monitoring Network contributes to establishing and supporting national marine baselines, and assisting with the management of Commonwealth and State marine reserves. &lt;br\/&gt;&lt;br\/&gt;Reef Life Survey (RLS) and the Australian Temperate Reef Network (ATRC) aims to improve biodiversity conservation and the sustainable management of marine resources by coordinating surveys of rocky and coral reefs using scientific methods, with the ultimate goal to improve coastal stewardship. Our activities depend on the skills of marine scientists, experienced and motivated recreational SCUBA divers, partnerships with management agencies and university researchers, and active input from the ATRC partners and RLS Advisory Committee.&lt;br\/&gt;&lt;br\/&gt;RLS and ATRC data are freely available to the public for non-profit purposes, so not only managers, but also groups such as local dive clubs or schools may use these data to look at changes over time in their own local reefs. By making data freely available and through public outputs, RLS and ATRC aims to raise broader community awareness of the status of Australia\u2019s marine biodiversity and associated conservation issues.","institutions":null,"researchers":null,"status":"other","fundingAmount":null,"fundingScheme":null,"startDate":null,"endDate":null,"dateTimeModified":"2025-07-02T19:50:58Z","dateTimeCreated":"2024-07-12T21:32:18Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":["8cdcdcad-399b-4bed-8cb2-29c486b6b124"],"subjects":["oceans","biota","environment","diver","Abundance of biota","Biotic taxonomic identification","National Reef Monitoring Network Sub-Facility, Integrated Marine Observing System (IMOS)","COMMUNITY DYNAMICS","KELP FOREST","CORAL REEF","FISH","PELAGIC"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/programs\/3012301"}]},{"id":"476691","key":"IMOS\/8cc13f98-9897-4193-8ba6-d1f05356d3f2","type":"project","title":"Argo float : a platform of the IMOS Argo Floats Facility","description":"Argo floats have revolutionised our understanding of the broad scale structure of the oceans to 2000 m depth. In the past 10 years more high resolution hydrographic profiles have been provided by Argo floats then from the rest of the observing system put together.&lt;br\/&gt;&lt;br\/&gt;Each Argo float is identified by a unique identification number called a WMO ID. WMO (World Meteorological Organisation) ID Numbers are assigned to measurement stations and observing platforms to enable researchers to keep track of, and uniquely identify their floats.&lt;br\/&gt;&lt;br\/&gt;Argo floats alter their buoyancy by using a battery pack and motor to drive oil from inside the float to an external bladder. This changes the floats volume and thus its density relative to the surrounding seawater allowing it to move up and down through the water column. &lt;br\/&gt;&lt;br\/&gt;A typical Argo float mission is to profile from 2000 m depth to the sea surface every 10 days. On deployment, the float sinks to a depth of 1000 m and drifts with the ocean currents for 9 days. Then the float sinks deeper to its profile depth (usually 2000 m) before starting to ascend through the water column measuring temperature, salinity and pressure as it rises. Once at the surface it transmits location and profile data via satellite to land-based Argo data centres. After transmission the float sinks again and repeats the cycle. &lt;br\/&gt;&lt;br\/&gt;The average life of the latest model APEX Argo floats are around 3.7 years or approximately 135 cycles. These statistics are for floats with the standard alkaline battery configuration from an analysis by Kobayashi et al (2009).In the Australian Argo program, the floats are deployed with a combination of lithium and alkaline battery packs which extends float lifetime. The Facility floats usually last 7 years and several floats are approaching their 9th birthday and are still returning good data.","researchers":["Oke, Peter"],"institutions":null,"status":"other","fundingAmount":null,"fundingScheme":null,"startDate":null,"endDate":null,"dateTimeModified":"2025-07-02T19:51:00Z","dateTimeCreated":"2014-11-24T12:51:24Z","funder":null,"managingInstitution":null,"principalInvestigator":["Oke, Peter"],"purl":null,"identifiers":["8cc13f98-9897-4193-8ba6-d1f05356d3f2"],"subjects":["oceans","WATER TEMPERATURE","EARTH SCIENCE","OCEANS","OCEAN TEMPERATURE","WATER DEPTH","BATHYMETRY\/SEAFLOOR TOPOGRAPHY","OCEAN CURRENTS","OCEAN CIRCULATION","SALINITY","SALINITY\/DENSITY","DISSOLVED GASES","OCEAN CHEMISTRY","WATER PRESSURE","OCEAN PRESSURE","Global \/ Oceans | World Ocean","Global \/ Oceans | Indian Ocean","Global \/ Oceans | Pacific Ocean","Global \/ Oceans | Southern Ocean","Regional Seas | Tasman Sea","IMOS Node | Bluewater and Climate","Profiling Float | Autonomous Profiling Float"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/projects\/476691"}]},{"id":"476862","key":"IMOS\/677a6c35-0c34-4479-afd3-cb0d2d091cfa","type":"program","title":"IMOS - Argo Floats Facility","description":"The Argo Floats Facility (formerly known as the Argo Australia), aims to undertake real time monitoring of the broad ocean state around Australia by maintaining an array of profiling (Argo) floats that measure temperature and salinity down to 2000m every 10 days in real time. This provides the essential and dominant in situ data stream for ocean and climate research and prediction\/re-analyses.&lt;br\/&gt;&lt;br\/&gt;The primary goal of the Argo program is to maintain a global array of autonomous profiling floats integrated with other elements of the climate observing system.&lt;br\/&gt;The specific aims are to:&lt;br\/&gt; - detect climate variability over seasonal to decadal time-scales including changes in the large-scale distribution of temperature and salinity and in the transport of these properties by large-scale ocean circulation.&lt;br\/&gt; - provide information needed for the calibration of satellite measurements.&lt;br\/&gt; - deliver data for the initialization and constraint of climate models.&lt;br\/&gt;&lt;br\/&gt;Argo Floats Facility is the third largest contributer to the global array (in terms of instrument numbers) after the Us and Japan.&lt;br\/&gt;&lt;br\/&gt;To ensure 50% of the minimum design coverage of 1 float every 3 x3 degrees of latitude\/longitude in the Australian region (i.e. between 90oE to 18oE, equator to Antarctic) requires deployment of 60 floats per year with the balance derived from international partners. The NCRIS investment along with currently identified Australian partners will provide for ~ 75 % of this requirement with further opportunities for co-investment. &lt;br\/&gt;&lt;br\/&gt;Work is underway to equip 30 floats per annum with oxygen sensors to address carbon cycle and biogeochemical cycling (BGC) variability in the Southern Ocean which is a significant component of the world climate and carbon cycling system. Additional investment would be required for this to occur.","researchers":["Oke, Peter"],"institutions":null,"status":"other","fundingAmount":null,"fundingScheme":null,"startDate":null,"endDate":null,"dateTimeModified":"2025-07-02T19:51:00Z","dateTimeCreated":"2014-11-24T12:51:36Z","funder":null,"managingInstitution":null,"principalInvestigator":["Oke, Peter"],"purl":null,"identifiers":["677a6c35-0c34-4479-afd3-cb0d2d091cfa"],"subjects":["oceans","WATER TEMPERATURE","EARTH SCIENCE","OCEANS","OCEAN TEMPERATURE","WATER DEPTH","BATHYMETRY\/SEAFLOOR TOPOGRAPHY","OCEAN CURRENTS","OCEAN CIRCULATION","SALINITY","SALINITY\/DENSITY","DISSOLVED GASES","OCEAN CHEMISTRY","WATER PRESSURE","OCEAN PRESSURE","Global \/ Oceans | World Ocean","Global \/ Oceans | Indian Ocean","Global \/ Oceans | Pacific Ocean","Global \/ Oceans | Southern Ocean","Regional Seas | Tasman Sea","IMOS Node | Bluewater and Climate","Profiling Float | Autonomous Profiling Float"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/programs\/476862"}]},{"id":"3012394","key":"IMAS\/8cdcdcad-399b-4bed-8cb2-29c486b6b124","type":"program","title":"IMOS - National Reef Monitoring Network Sub-Facility","description":"The National Reef Monitoring Network brings together shallow reef surveys conducted around Australia into a centralised database. The IMOS National Reef Monitoring Network sub-Facility collates, cleans, stores and makes this data rapidly available from contributors including: Reef Life Survey, Parks Australia, Department of Biodiversity, Conservation and Attractions (Western Australia), Department of Environment, Water and Natural Resources (South Australia), Department of Primary Industries (New South Wales), Tasmanian Parks and Wildlife Service and Parks Victoria.&lt;br\/&gt;&lt;br\/&gt;The data provided by the National Reef Monitoring Network contributes to establishing and supporting national marine baselines, and assisting with the management of Commonwealth and State marine reserves. &lt;br\/&gt;&lt;br\/&gt;Reef Life Survey (RLS) and the Australian Temperate Reef Network (ATRC) aims to improve biodiversity conservation and the sustainable management of marine resources by coordinating surveys of rocky and coral reefs using scientific methods, with the ultimate goal to improve coastal stewardship. Our activities depend on the skills of marine scientists, experienced and motivated recreational SCUBA divers, partnerships with management agencies and university researchers, and active input from the ATRC partners and RLS Advisory Committee.&lt;br\/&gt;&lt;br\/&gt;RLS and ATRC data are freely available to the public for non-profit purposes, so not only managers, but also groups such as local dive clubs or schools may use these data to look at changes over time in their own local reefs. By making data freely available and through public outputs, RLS and ATRC aims to raise broader community awareness of the status of Australia\u2019s marine biodiversity and associated conservation issues.","institutions":null,"researchers":null,"status":"other","fundingAmount":null,"fundingScheme":null,"startDate":null,"endDate":null,"dateTimeModified":"2025-07-01T10:20:31Z","dateTimeCreated":"2024-07-12T21:35:27Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":["8cdcdcad-399b-4bed-8cb2-29c486b6b124"],"subjects":["oceans","biota","environment","diver","Abundance of biota","Biotic taxonomic identification","National Reef Monitoring Network Sub-Facility, Integrated Marine Observing System (IMOS)","COMMUNITY DYNAMICS","KELP FOREST","CORAL REEF","FISH","PELAGIC"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/programs\/3012394"}]},{"id":"1730400","key":"IMAS\/4b5ae6b0-36b2-11dd-9409-00188b4c0af8","type":"program","title":"Reef Life Survey: Linking volunteer divers, scientists and managers in marine research and conservation - WEBSITE","description":"Reef Life Survey is a program that trains and assists a network of skilled and committed recreational divers to cost-effectively assess the state of the inshore marine environment at the continental scale. The program uses standardised underwater visual census methods employed by SCUBA divers to survey fish and invertebrate species and to record macroalgal and coral cover using photo quadrats - this record refers to the website for this program.&lt;br\/&gt;&lt;br\/&gt;By standardising techniques and establishing a monitoring system on a nation-wide scale, the program addresses many of the current problems associated with managing the marine environment, including the paucity, patchiness and variable quality of data on the distribution of and trends to marine biodiversity. &lt;br\/&gt;&lt;br\/&gt;A central database is managed for the storage, analysis and dissemination of data collected nationally, with a publicly-accessible web-based portal. The website allows information collected on Australia's marine environment to be accessed in a meaningful form by policy-makers and the general public, including recreational groups, scientists and industry. It also has information and resources for particpating divers and those wishing to become involved.&lt;br\/&gt;&lt;br\/&gt;The dataset generated by recreational divers will provide a national framework for monitoring the state of the inshore environment and the identification of those threats and locations of greatest conservation concern.&lt;br\/&gt;&lt;br\/&gt;&lt;br\/&gt;This record points to the online resource for Reef Life Survey:&lt;br\/&gt;&lt;br\/&gt;http:\/\/www.reeflifesurvey.com\/","institutions":["Institute for Marine and Antarctic Studies (IMAS), University of Tasmania (UTAS)","Tasmanian Aquaculture and Fisheries Institute (TAFI)"],"researchers":null,"status":"other","fundingAmount":null,"fundingScheme":null,"startDate":2007,"endDate":null,"dateTimeModified":"2025-07-01T10:20:21Z","dateTimeCreated":"2021-07-16T12:28:18Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":["www.reeflifesurvey.com\/","4b5ae6b0-36b2-11dd-9409-00188b4c0af8"],"subjects":["biota","FISH","EARTH SCIENCE","BIOLOGICAL CLASSIFICATION","ANIMALS\/VERTEBRATES","ECHINODERMS","ANIMALS\/INVERTEBRATES","CRUSTACEANS","ARTHROPODS","MOLLUSKS","REEF HABITAT","BIOSPHERE","AQUATIC ECOSYSTEMS","Biosphere | Vegetation | Macroalgae","Marine and Estuarine Ecology","Community Ecology","BIOLOGICAL SCIENCES","ECOLOGY","Temperate Reef","Tropical Reef"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/programs\/1730400"}]},{"id":"74667","key":"http:\/\/purl.org\/au-research\/grants\/arc\/LP0990329","type":"grant","title":"Withholding and withdrawing life-sustaining treatment from adults lacking capacity: Enhancing medical decision-making through doctors' compliance with the law","description":"Withholding and withdrawing life-sustaining treatment from adults lacking capacity: Enhancing medical decision-making through doctors' compliance with the law. This project will enhance medical decision-making about the provision of life-sustaining treatment to adults without decision-making capacity through improved compliance with the law. This will advance patients' autonomy and dignity, protect vulnerable adults whose lives may be wrongly ended because of inappropriate treatment decisions and avoid litigation for doctors and hospitals. The project also aims to improve the quality of the law by resolving legal ambiguity and proposing reforms. This will further enhance the quality of decision-making, and will reduce defensive medicine and the cost of complying with the law, leading to savings in health expenditure.","institutions":["Queensland University of Technology"],"researchers":["Ben White","Emeritus Professor Gail Williams","Prof Colleen Cartwright","Prof Lindy Willmott","Prof Malcolm Parker"],"status":"CLOSED","fundingAmount":287000,"fundingScheme":"Linkage Projects","startDate":2010,"endDate":2014,"dateTimeModified":"2025-07-16T15:10:21Z","dateTimeCreated":"2013-05-15T13:36:03Z","funder":["Australian Research Council"],"managingInstitution":["Queensland University of Technology","Queensland University of Technology","Queensland University of Technology"],"principalInvestigator":["Ben White","Emeritus Professor Gail Williams","Prof Colleen Cartwright","Prof Lindy Willmott","Prof Malcolm Parker"],"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/LP0990329","identifiers":["https:\/\/purl.org\/au-research\/grants\/arc\/LP0990329","LP0990329"],"subjects":["LAW","LAW AND LEGAL STUDIES","321212","Curriculum and pedagogy not elsewhere classified","Curriculum and pedagogy","EDUCATION","Professional education and training","Education systems","730203","730299","750599"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/74667"}]},{"id":"2907226","key":"http:\/\/purl.org\/au-research\/grants\/arc\/DP240100330","type":"grant","title":"Discovery Projects - Grant ID: DP240100330","description":"Early-life climate sensitivity: direct and indirect mechanisms. This project aims to investigate how climate change threatens animal populations by determining the mechanisms causing DNA damage (short telomeres) in nestling birds growing up in hot conditions. Telomeres are biomarkers of individual life expectancy, and short telomeres in young birds predict a decline in future population viability. Our project aims to determine the importance for heat-induced telomere shortening of: (1) nestling heat stress responses; (2) inheritance of heat-shortened sperm telomeres; and (3) parental buffering of heat effects. Expected benefits include enhanced reliability of climate change predictions and improved ability to identify climate change mitigation strategies before population declines are evident.","institutions":["Monash University"],"researchers":["Dr Anne-Marie Peters","Dr Melissah Rowe","Prof Dr Simon Verhulst"],"status":"ACTIVE","fundingAmount":662704,"fundingScheme":"Discovery Projects","startDate":2024,"endDate":2027,"dateTimeModified":"2025-07-16T15:07:59Z","dateTimeCreated":"2024-02-06T16:05:46Z","funder":["Australian Research Council"],"managingInstitution":["Monash University","Monash University","Monash University"],"principalInvestigator":["Dr Anne-Marie Peters","Dr Melissah Rowe","Prof Dr Simon Verhulst"],"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/DP240100330","identifiers":["https:\/\/purl.org\/au-research\/grants\/arc\/DP240100330","DP240100330"],"subjects":["Ecology","BIOLOGICAL SCIENCES","Behavioural ecology","Ecological impacts of climate change and ecological adaptation","Climate change impacts and adaptation","ENVIRONMENTAL SCIENCES","Expanding knowledge in the biological sciences","Expanding knowledge","EXPANDING KNOWLEDGE"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/2907226"}]},{"id":"81286","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/954117","type":"grant","title":"Skin tone measurement by reflectometer versusmelanin de nsity of the epidermis","institutions":["University of Tasmania"],"researchers":["Prof Terence Dwyer"],"description":null,"status":"CLOSED","fundingAmount":57835.25,"fundingScheme":"NHMRC Project Grants","startDate":1995,"endDate":1996,"dateTimeModified":"2015-05-06T16:12:41Z","dateTimeCreated":"2013-05-15T14:46:59Z","funder":["National Health and Medical Research Council"],"managingInstitution":["University of Tasmania"],"principalInvestigator":null,"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/954117","identifiers":["954117","https:\/\/purl.org\/au-research\/grants\/nhmrc\/954117"],"subjects":["histopathology","reflectometer","melanin density","skin type","skin colour","Public Health","Epidemiology","MEDICAL AND HEALTH SCIENCES","PUBLIC HEALTH AND HEALTH SERVICES"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/81286"}]},{"id":"113887","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/301295","type":"grant","title":"Seclusion: Perceptions of Aboriginal and Torres Strait Islander People","researchers":["Mr Derek Chong"],"description":null,"institutions":null,"status":"CLOSED","fundingAmount":25853,"fundingScheme":"NHMRC Postgraduate Scholarships","startDate":2004,"endDate":2004,"dateTimeModified":"2017-07-11T08:55:14Z","dateTimeCreated":"2013-05-15T17:26:46Z","funder":["National Health and Medical Research Council"],"managingInstitution":null,"principalInvestigator":["Mr Derek Chong"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/301295","identifiers":["301295","https:\/\/purl.org\/au-research\/grants\/nhmrc\/301295"],"subjects":["321207","aboriginal health","mental health","psychiatry","seclusion"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/113887"}]},{"id":"114072","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/327401","type":"grant","title":"Mechanisms of cytoprotection from oxidative stress in endothelial cells","institutions":["The University of Melbourne","University of Melbourne"],"researchers":["Dr Hitesh Peshavariya"],"description":null,"status":"CLOSED","fundingAmount":64340.64,"fundingScheme":"NHMRC Postgraduate Scholarships","startDate":2005,"endDate":2008,"dateTimeModified":"2015-05-06T16:11:39Z","dateTimeCreated":"2013-05-15T17:27:02Z","funder":["National Health and Medical Research Council"],"managingInstitution":["The University of Melbourne","University of Melbourne"],"principalInvestigator":["Dr Hitesh Peshavariya"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/327401","identifiers":["327401","https:\/\/purl.org\/au-research\/grants\/nhmrc\/327401"],"subjects":["Cardiology (incl. Cardiovascular Diseases)","MEDICAL AND HEALTH SCIENCES","CARDIORESPIRATORY MEDICINE AND HAEMATOLOGY","atherosclerosis","endothelial cells","nitiric oxide","prostacyclin","stroke"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/114072"}]},{"id":"95422","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/954605","type":"grant","title":"Obesity diabetes and cardiovascular diseases in Aborigi nes and Torres Strait Islanders","institutions":["Monash University"],"researchers":["Prof Kerin O'Dea"],"description":null,"status":"CLOSED","fundingAmount":1067057.1,"fundingScheme":"Program","startDate":1995,"endDate":1999,"dateTimeModified":"2015-05-06T15:37:13Z","dateTimeCreated":"2013-05-15T15:56:45Z","funder":["National Health and Medical Research Council"],"managingInstitution":["Monash University","Monash University","Monash University"],"principalInvestigator":null,"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/954605","identifiers":["954605","https:\/\/purl.org\/au-research\/grants\/nhmrc\/954605"],"subjects":["epidemiology","obesity","heart disease","diabetes","aboriginal health","Public Health","Cardiovascular diseases & sciences"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/95422"}]},{"id":"1317280","key":"http:\/\/purl.org\/au-research\/grants\/arc\/FL170100020","type":"grant","title":"Australian Laureate Fellowships - Grant ID: FL170100020","description":"Advances in index theory and applications. The project aims to develop novel techniques to investigate Geometric analysis on infinite dimensional bundles, as well as Geometric analysis of pathological spaces with Cantor set as fibre, that arise in models for the fractional quantum Hall effect and topological matter, areas recognised with the 1998 and 2016 Nobel Prizes. Building on the applicant&#8217;s expertise in the area, the project will involve postgraduate and postdoctoral training in order to enhance Australia&#8217;s position at the forefront of international research in Geometric Analysis. Ultimately, the project will enhance Australia's leading position in the area of Index Theory by developing novel techniques to solve challenging conjectures, and mentoring HDR students and ECRs.","institutions":["The University of Adelaide"],"researchers":null,"status":"CLOSED","fundingAmount":1638060,"fundingScheme":"Australian Laureate Fellowships","startDate":2018,"endDate":2025,"dateTimeModified":"2025-07-16T15:04:54Z","dateTimeCreated":"2018-03-07T10:37:38Z","funder":["Australian Research Council"],"managingInstitution":["The University of Adelaide"],"principalInvestigator":null,"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/FL170100020","identifiers":["FL170100020","https:\/\/purl.org\/au-research\/grants\/arc\/FL170100020"],"subjects":["PURE MATHEMATICS","MATHEMATICAL SCIENCES","Algebraic and Differential Geometry","Operator Algebras and Functional Analysis","Partial Differential Equations","Expanding Knowledge in the Mathematical Sciences","EXPANDING KNOWLEDGE","EXPANDING KNOWLEDGE"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/1317280"}]},{"id":"947026","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/1122816","type":"grant","title":"Neural trajectories towards vulnerability versus resilience: A longitudinal twin study","description":"Resilience not only defines the absence of mental disorder; it defines the ability to positively adapt in the face of adversity. Due to this conceptual ambiguity, little is known of its underlying neurobiology as compared to symptoms like depression and anxiety. This knowledge would aid the development of effective interventions following trauma exposure. We aim to define the first neural profile of resilience in 270 adults, using the twin method to decide novel gene-environment influences.","institutions":["University of New South Wales"],"researchers":["Dr Justine Gatt","Dr Robin Turner","Prof Leanne Williams"],"status":"CLOSED","fundingAmount":1292995.4,"fundingScheme":"Project Grants","startDate":2017,"endDate":2022,"dateTimeModified":"2018-03-08T23:00:02Z","dateTimeCreated":"2017-07-05T17:46:56Z","funder":["National Health and Medical Research Council"],"managingInstitution":["University of New South Wales","University of New South Wales"],"principalInvestigator":["Dr Justine Gatt"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/1122816","identifiers":["1122816","https:\/\/purl.org\/au-research\/grants\/nhmrc\/1122816"],"subjects":["Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)","PSYCHOLOGY AND COGNITIVE SCIENCES","PSYCHOLOGY","resilience","anxiety","depression","twins","brain imaging"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/947026"}]},{"id":"1345602","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1085062","type":"grant","title":"Trial to Evaluate Anti-fibrinolytic Therapy in Thrombocytopenia (TREATT)","description":"Patients with haematologic malignancies often have low platelet counts from their disease or treatment. This can be associated with bleeding, which can sometimes be serious or fatal. Nearly 2\/3 of all platelet transfusions in Australia are given in this setting to try to prevent bleeding but many people still experience bleeding. This study asks whether tranexamic acid can safely & effectively reduce bleeding and if it does, does reduced bleeding lead to reduction in platelet transfusions?","institutions":["Monash University"],"researchers":["A\/Pr David Westerman","A\/Pr Erica Wood","A\/Pr Merrole Cole-Sinclair","Dr Lise Estcourt","Dr Simon Stanworth","Dr Zoe McQuilten","Prof Jeff Szer"],"status":"ACTIVE","fundingAmount":1012635,"fundingScheme":"Project Grants","startDate":2015,"endDate":null,"dateTimeModified":"2019-06-03T14:23:18Z","dateTimeCreated":"2018-10-03T11:49:36Z","funder":["National Health and Medical Research Council"],"managingInstitution":["Monash University","Monash University","Monash University"],"principalInvestigator":["A\/Pr Erica Wood"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1085062","identifiers":["GNT1085062","https:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1085062"],"subjects":["Clinical Medicine and Science","haematological malignancy | blood transfusion | platelets | cancer treatment | supportive care"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/1345602"}]},{"id":"15348","key":"www.une.edu.au:herbarium:ands:Veg-NENP-01","type":"project","title":"The vegetation and plant species of New England National Park","description":"&lt;p&gt;&lt;em&gt;A major study of vegetation and flora of New England National Parks undertaken for the New South Wales National Parks and Wildlife Service.&lt;\/em&gt;&lt;\/p&gt;","institutions":["N.C.W. Beadle Herbarium"],"researchers":null,"status":"CLOSED","fundingAmount":null,"fundingScheme":null,"startDate":1998,"endDate":2000,"dateTimeModified":"2018-03-13T10:26:32Z","dateTimeCreated":"2013-05-14T17:03:30Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":["www.une.edu.au:herbarium:ands:Veg-NENP-01"],"subjects":["Vegetation","Plant Ecology","Terrestrial Ecology","BIOLOGICAL SCIENCES","ECOLOGY","Flora","Biogeography and Phylogeography","EVOLUTIONARY BIOLOGY","Environmental Management","ENVIRONMENTAL SCIENCES","ENVIRONMENTAL SCIENCE AND MANAGEMENT"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/projects\/15348"}]},{"id":"1344487","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1047291","type":"grant","title":"Preventing anxiety, depression and substance use in adolescents.","description":"Anxiety, depressive and substance use disorders account for three quarters of the disability attributed to mental disorders. Yet we have few models of well-implemented prevention programs for these common disorders. The current proposal addresses this gap by evaluating an innovative internet-based approach to preventing mental health and substance use problems in Australian adolescents.","researchers":["A\/Pr Nicola Newton","A\/Pr Timothy Slade","Dr Catherine Chapman","Dr Nyanda McBride","Prof Gavin Andrews","Prof Leanne Hides","Prof Maree Teesson","Prof Steve Allsop"],"institutions":null,"status":"ACTIVE","fundingAmount":1709988,"fundingScheme":"Targeted Calls for Research","startDate":2012,"endDate":null,"dateTimeModified":"2019-06-03T14:23:11Z","dateTimeCreated":"2018-10-03T11:49:26Z","funder":["National Health and Medical Research Council"],"managingInstitution":null,"principalInvestigator":["Prof Maree Teesson"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1047291","identifiers":["GNT1047291","https:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1047291"],"subjects":["Public Health","anxiety | depression | alcohol | substance use | prevention | internet"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/1344487"}]},{"id":"550868","key":"http:\/\/purl.org\/au-research\/grants\/arc\/DP110101362","type":"grant","title":"A theoretical hierachy to investigate the electronic behaviour of graphene nanostructures under realistic conditions","description":"A theoretical hierachy to investigate the electronic behaviour of graphene nanostructures under realistic conditions. One of the most exciting new nano-materials is graphene which promises to be the basis of a new industry producing nano-electronics and nano-devices such as chemical sensors. This project aims to provide sound scientific knowledge on the effects of environmental conditions on the properties of graphene which are vital for its industrial use.","institutions":["RMIT University"],"researchers":["Amanda Barnard","Prof Ian Snook"],"status":"CLOSED","fundingAmount":240000,"fundingScheme":"Discovery Projects","startDate":2011,"endDate":2013,"dateTimeModified":"2025-07-16T15:09:20Z","dateTimeCreated":"2015-04-29T16:59:02Z","funder":["Australian Research Council"],"managingInstitution":["RMIT University","RMIT University"],"principalInvestigator":["Amanda Barnard","Prof Ian Snook"],"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/DP110101362","identifiers":["https:\/\/purl.org\/au-research\/grants\/arc\/DP110101362","DP110101362"],"subjects":["CONDENSED MATTER PHYSICS","PHYSICAL SCIENCES","Condensed Matter Modelling and Density Functional Theory","Theoretical and Computational Chemistry not elsewhere classified","CHEMICAL SCIENCES","THEORETICAL AND COMPUTATIONAL CHEMISTRY","Nanotechnology not elsewhere classified","TECHNOLOGY","NANOTECHNOLOGY","Expanding Knowledge in the Physical Sciences","EXPANDING KNOWLEDGE","EXPANDING KNOWLEDGE","Expanding Knowledge in the Chemical Sciences"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/550868"}]},{"id":"1344159","key":"http:\/\/purl.org\/au-research\/grants\/arc\/LP170100979","type":"grant","title":"Linkage Projects - Grant ID: LP170100979","description":"On-demand visible light degradable dental materials. This project aims to break new ground in the field of advanced adhesives by pioneering a unique system that can be cleaved with a defined visible light trigger, enabling the removal of previously bonded material without mechanical force. This would allow two materials to be strongly bonded, including dental crowns, braces and implants. The project will advance on-demand degradable materials design, introducing an advanced class of responsive networks for applications where reversible bonding is critical. It will have flow on benefits in future dental material applications and also have applications where simple-to-remove, temporary adhesives are required.","institutions":["Queensland University of Technology"],"researchers":["Dr Andreas-Neil Unterreiner","Dr Yohann Catel","Eva Blasco","James Blinco","Professor Christopher Barner-Kowollik"],"status":"CLOSED","fundingAmount":364503,"fundingScheme":"Linkage Projects","startDate":2018,"endDate":2022,"dateTimeModified":"2025-07-16T15:04:31Z","dateTimeCreated":"2018-10-02T14:21:15Z","funder":["Australian Research Council"],"managingInstitution":["Queensland University of Technology","Queensland University of Technology","Queensland University of Technology"],"principalInvestigator":["Dr Andreas-Neil Unterreiner","Dr Yohann Catel","Eva Blasco","James Blinco","Professor Christopher Barner-Kowollik"],"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/LP170100979","identifiers":["https:\/\/purl.org\/au-research\/grants\/arc\/LP170100979","LP170100979"],"subjects":["MACROMOLECULAR AND MATERIALS CHEMISTRY","CHEMICAL SCIENCES","Chemical Characterisation of Materials","Synthesis of Materials","Rubber and Synthetic Resins","MANUFACTURING","INDUSTRIAL CHEMICALS AND RELATED PRODUCTS"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/1344159"}]},{"id":"2913457","key":"http:\/\/purl.org\/au-research\/grants\/arc\/DP220100988","type":"grant","title":"Discovery Projects - Grant ID: DP220100988","description":"Digital Transaction Platforms in Asia. This project seeks to provide a comprehensive and authoritative account of the rapid shift towards digital payments in Asian economies. The study examines the technical and commercial organisation of the leading Asian transaction platforms. Our approach seeks to emphasise the significance of cultural diversity in Asian markets through detailed studies of everyday norms and practices in India , Indonesia, China, Japan, Malaysia, Singapore, Vietnam and the Philippines. A large scale analysis of market and user data seeks to illustrate key trends at scale and provide a regional knowledge base for assessing the implications for Australia, fostering multilateral collaboration and developing robust policy recommendations on the digital economy.\\n","identifier_type":null,"identifier_value":null,"institutions":null,"researchers":null,"status":"ACTIVE","fundingAmount":492708,"fundingScheme":"Discovery Projects","startDate":2022,"endDate":2026,"dateTimeModified":"2025-07-16T15:02:20Z","dateTimeCreated":"2024-02-06T16:22:38Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":null,"subjects":["COMMUNICATION AND MEDIA STUDIES","LANGUAGE, COMMUNICATION AND CULTURE","Communication Technology and Digital Media Studies","Asian Cultural Studies","CULTURAL STUDIES","Media Services not elsewhere classified","INFORMATION AND COMMUNICATION SERVICES","MEDIA SERVICES","International Political Economy (excl. International Trade)","LAW, POLITICS AND COMMUNITY SERVICES","INTERNATIONAL RELATIONS"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/2913457"}]},{"id":"116346","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/606770","type":"grant","title":"Brain regions and mechanisms mediating cardiorespiratory control and arousal from sleep","institutions":["Monash University"],"researchers":["Miss Heidi Richardson"],"description":null,"status":"CLOSED","fundingAmount":233112.88,"fundingScheme":"Early Career Fellowships","startDate":2010,"endDate":2012,"dateTimeModified":"2015-05-06T16:16:41Z","dateTimeCreated":"2013-05-15T17:31:44Z","funder":["National Health and Medical Research Council"],"managingInstitution":["Monash University","Monash University","Monash University"],"principalInvestigator":["Miss Heidi Richardson"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/606770","identifiers":["606770","https:\/\/purl.org\/au-research\/grants\/nhmrc\/606770"],"subjects":["Paediatrics","MEDICAL AND HEALTH SCIENCES","PAEDIATRICS AND REPRODUCTIVE MEDICINE","Cardiorespiratory Control Mechanisms","Mechanisms for Sudden Infant Death Syndrome","Neuroimaging"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/116346"}]},{"id":"1346925","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1114760","type":"grant","title":"PANDORA Wave 1: Assessment of the impact of maternal diabetes on growth and nutritional indicators, cardio-metabolic risk factors and developmental risk of pre-school aged children living in the Northern Territory.","description":"Addressing the diabetes epidemic in the Indigenous Australian population requires early intervention. Early life is critical for long term risk of chronic disease but little is known regarding effective interventions, particularly for follow-up of children after a pregnancy complicated by diabetes. The project examines growth, body composition, and risk of developmental issues in children of mothers with and without diabetes in pregnancy, exploring risk factors for later chronic disease.","institutions":["Menzies School of Health Research"],"researchers":["Dr Angela Titmuss"],"status":"CLOSED","fundingAmount":122714,"fundingScheme":"Postgraduate Scholarships","startDate":2016,"endDate":2019,"dateTimeModified":"2018-10-03T17:39:44Z","dateTimeCreated":"2018-10-03T11:49:49Z","funder":["National Health and Medical Research Council"],"managingInstitution":["Menzies School of Health Research","Menzies School of Health Research"],"principalInvestigator":["Dr Angela Titmuss"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1114760","identifiers":["GNT1114760","https:\/\/purl.org\/au-research\/grants\/nhmrc\/GNT1114760"],"subjects":["Paediatrics","MEDICAL AND HEALTH SCIENCES","PAEDIATRICS AND REPRODUCTIVE MEDICINE","diabetes mellitus","anthropometry","maternal and child health","developmental outcomes"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/1346925"}]},{"id":"533771","key":"http:\/\/purl.org\/au-research\/grants\/arc\/LP120100359","type":"grant","title":"Geochemistry of ore metals at very high temperatures","description":"Geochemistry of ore metals at very high temperatures. The world&#8217;s largest copper and gold mines occur in extinct volcanoes around the Pacific Rim. Understanding how these essential metals are mobilised from magmas in the roots of volcanoes to become ore deposits and how to recognize where this has occurred is crucial in exploration for new deposits.","institutions":["Australian National University","The Australian National University"],"researchers":["Dr Richard Henley","John Mavrogenes"],"status":"CLOSED","fundingAmount":220000,"fundingScheme":"Linkage Projects","startDate":2012,"endDate":2014,"dateTimeModified":"2025-07-16T15:08:30Z","dateTimeCreated":"2015-04-15T15:07:56Z","funder":["Australian Research Council"],"managingInstitution":["Australian National University","The Australian National University","The Australian National University"],"principalInvestigator":["Dr Richard Henley","John Mavrogenes"],"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/LP120100359","identifiers":["https:\/\/purl.org\/au-research\/grants\/arc\/LP120100359","LP120100359"],"subjects":["GEOCHEMISTRY","EARTH SCIENCES","Exploration Geochemistry","Inorganic Geochemistry","Isotope Geochemistry","Copper Ore Exploration","MINERAL RESOURCES (EXCL. ENERGY RESOURCES)","MINERAL EXPLORATION","Precious (Noble) Metal Ore Exploration"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/533771"}]},{"id":"95559","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/300454","type":"grant","title":"A prospective cohort study of mortality, abstinence, criminality and psychiatric comorbidity","description":"Over 70 000 Australians are dependent on heroin. Heroin dependence is remarkably persistent and is, in many cases, a lifelong condition. Long term treatment outcome and abstinence from heroin among this group are poor. Mortality among heroin users is high, with heroin users dying at a rate 13 times that of peers. Despite the extent of the problem, the natural history of heroin users has not yet been studied in Australia. The current study will be the first Australian study of the natural history of heroin users. The study will follow up a large cohort of heroin users over a three year period. Estimates will be obtained of mortality rates, abstinence rates, criminal careers, and psychiatric problems among heroin users. It will also examine factors that predict abstinence, mortality, criminality and levels of psychopathology, and determine the health costs associated with heroin use careers. The study will provide essential data on how heroin use progresses, and on what factors predict a better outcome for heroin users.","researchers":["Dr Joanne Ross","Prof Maree Teesson","Prof Michael Lynskey","Prof Shane Darke"],"institutions":null,"status":"CLOSED","fundingAmount":419500,"fundingScheme":"NHMRC Project Grants","startDate":2004,"endDate":2005,"dateTimeModified":"2017-07-11T08:30:19Z","dateTimeCreated":"2013-05-15T15:56:53Z","funder":["National Health and Medical Research Council"],"managingInstitution":null,"principalInvestigator":["Prof Maree Teesson"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/300454","identifiers":["300454","https:\/\/purl.org\/au-research\/grants\/nhmrc\/300454"],"subjects":["321021","Longitudinal study","Mortality","Opioid dependence","Psychiatric disorders","Treatment","Addictive behaviours","Drug addiction","Overdose","Psychiatric morbidity"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/95559"}]},{"id":"66368","key":"http:\/\/purl.org\/au-research\/grants\/arc\/LP0776653","type":"grant","title":"The Impact on the Human Rights of Asylum-Seekers and Host Communities of Australia's Border Control Cooperation with Indonesia and PNG","description":"The Impact on the Human Rights of Asylum-Seekers and Host Communities of Australia's Border Control Cooperation with Indonesia and PNG. Australia regards border control cooperation with Indonesia and PNG as vital for preventing irregular entry into its own territory. Little is known, however, about the implications of cooperation for asylum-seekers or their host communities in Indonesia and PNG. This project is of national benefit because it advances knowledge by investigating whether Australia can more effectively safeguard the human rights of asylum-seekers and others affected by its regional border control cooperation. The results of this study will enhance the capacity of policy makers to deal with mixed flows of irregular migrants and asylum-seekers consistently with human rights and thus Australia's ability to play a positive leadership role in its region.","institutions":["La Trobe University"],"researchers":["Prof Sandra Gifford","Savitri Taylor"],"status":"CLOSED","fundingAmount":67965,"fundingScheme":"Linkage Projects","startDate":2007,"endDate":2009,"dateTimeModified":"2025-07-16T15:11:40Z","dateTimeCreated":"2013-05-15T12:06:01Z","funder":["Australian Research Council"],"managingInstitution":["La Trobe University","La Trobe University"],"principalInvestigator":["Prof Sandra Gifford","Savitri Taylor"],"purl":"https:\/\/purl.org\/au-research\/grants\/arc\/LP0776653","identifiers":["https:\/\/purl.org\/au-research\/grants\/arc\/LP0776653","LP0776653"],"subjects":["LAW","LAW AND LEGAL STUDIES","360105","Physical education and development curriculum and pedagogy","Curriculum and pedagogy","EDUCATION","Higher education","Education systems","750599","750704"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/66368"}]},{"id":"82851","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/961170","type":"grant","title":"Signal transduction in macrophages","institutions":["The University of Queensland","University of Queensland"],"researchers":["Prof David A Hume"],"description":null,"status":"CLOSED","fundingAmount":189087.1,"fundingScheme":"NHMRC Project Grants","startDate":1996,"endDate":1998,"dateTimeModified":"2015-05-06T16:19:01Z","dateTimeCreated":"2013-05-15T14:47:54Z","funder":["National Health and Medical Research Council"],"managingInstitution":["The University of Queensland","University of Queensland"],"principalInvestigator":null,"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/961170","identifiers":["961170","https:\/\/purl.org\/au-research\/grants\/nhmrc\/961170"],"subjects":["ets","urokinase","transcription","macrophage","csf-1","Basic Science","Biochemistry & Clinical Chemistry"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/82851"}]},{"id":"76962","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/107345","type":"grant","title":"Evaluation of specificity, mechanism of action and therapeutic use of peptides that disrupt T-cell antigen receptor","description":"Molecular disorganisation of receptor assembly renders the receptor incompetent and the cell unable to perform its normal function. In autoimmune diseases where the target is self the ability to stop autoreactive T cells is a therapy. Synthetic compounds known as peptides have been developed in our laboratory with the ability to disrupt cell function and we are at the forefront of such research. We hypothesise that if you prevent the receptor from assembling properly then it will not function. The end result is the potential to develop novel drugs with new means to treat inflammation in a number of autoimmune disorders including diabetes, rheumatoid arthritis, multiple sclerosis and psoriasis. Application of this concept is not restricted to immunology or the disruption of the T-cell antigen receptor but has wider therapeutic application to other multicomponent receptors relevant in the field of oncology, endocrinology, and allergy. By design one can produce peptides that will specifically inhibit specific cellular functions based on structure-function relationships. Further research into this area will then allow design of new non-peptide chemical entities based on the original peptide sequence and structure with easier pharmacological handling properties and efficacy. This project aims to define necessary features of the peptide and test it in humans.","researchers":["Prof Nicholas Manolios"],"institutions":null,"status":"CLOSED","fundingAmount":166885.69,"fundingScheme":"NHMRC Project Grants","startDate":2000,"endDate":2002,"dateTimeModified":"2017-07-11T08:19:47Z","dateTimeCreated":"2013-05-15T13:42:37Z","funder":["National Health and Medical Research Council"],"managingInstitution":null,"principalInvestigator":["Prof Nicholas Manolios"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/107345","identifiers":["107345","https:\/\/purl.org\/au-research\/grants\/nhmrc\/107345"],"subjects":["321028","Autoimmune diseases eg rheumatoid arthritis, MS","New biological approach for receptor dysfunction","Peptides as therapeutic agents","T cell antigen receptor","T cells","New method for drug design","Preventive therapy","Treatment of autoimmune diseases, eg RA, MS, psoriasis"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/76962"}]},{"id":"3663523","key":"http:\/\/purl.org\/au-research\/grants\/arc\/IE240100180","type":"grant","title":"Early Career Industry Fellowships - Grant ID: IE240100180","description":"Smart graphene supercapacitors for self-sustained and zero-emission gyms. This project aims to develop a smart and robust graphene supercapacitor system (GraFit) that harnesses the green electricity generated by gym-users to power the self-sustained and zero-emission gyms. This project expects to generate new knowledge in translating graphene supercapacitors into real-life applications. Expected outcomes include a practical GraFit system ideally compatible with the intermittent and fluctuating electricity generated from gym workouts. The establishment of the world's first self-sustained and zero-emission gym innovatively collects and uses the massive kinetic energy previously dumped through gym. It promotes deep decarbonisation in Australian fitness industry and green and healthy lifestyles in Australian society.","identifier_type":null,"identifier_value":null,"institutions":null,"researchers":null,"status":"ACTIVE","fundingAmount":450000,"fundingScheme":"Early Career Industry Fellowships","startDate":2024,"endDate":2027,"dateTimeModified":"2025-07-16T15:07:54Z","dateTimeCreated":"2025-07-16T15:07:54Z","funder":null,"managingInstitution":null,"principalInvestigator":null,"purl":null,"identifiers":null,"subjects":["Electrical engineering","ENGINEERING","Electrical energy generation (incl. renewables, excl. photovoltaics)","Electrical energy storage","Functional materials","Materials engineering","Energy systems and analysis","Energy storage, distribution and supply","ENERGY","Energy storage, distribution and supply not elsewhere classified","Renewable energy not elsewhere classified","Renewable energy"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/3663523"}]},{"id":"101037","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/951428","type":"grant","title":"as above","researchers":["Prof Anthony J F D'Apice"],"description":null,"institutions":null,"status":"CLOSED","fundingAmount":4500,"fundingScheme":"NHMRC Infrastructure Grants","startDate":1995,"endDate":1995,"dateTimeModified":"2015-05-06T16:00:49Z","dateTimeCreated":"2013-05-15T16:57:33Z","funder":["National Health and Medical Research Council"],"managingInstitution":null,"principalInvestigator":null,"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/951428","identifiers":["951428","https:\/\/purl.org\/au-research\/grants\/nhmrc\/951428"],"subjects":["Not Applicable"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/101037"}]},{"id":"94547","key":"http:\/\/purl.org\/au-research\/grants\/nhmrc\/284421","type":"grant","title":"Characterisation of a novel direct electrochemical chip as a biosensor and tool for studying redox-sensitive proteins","description":"Biosensors use biomolecules to detect a chemical event. They are becoming important for the rapid and reliable measurement of the concentrations of molecules in fluids. In human medicine they will be of great use to general practitioners and patients for instantaneous read outs of concentrations of many different biological molecules. How well a biosensor responds depends on the method in which the biomolecule is immobilised to a surface and the signal detected. We have made a significant advance in biosensing capabilities using a recombinant protein (thioredoxin) and demonstrated the improvement that is possible by (i) immobilising the protein in a highly oriented way and (ii) using a sensitive electrical signal to monitor the response. Here we will undertake more comprehensive testing by extending the number of proteins to include the 4 major classes of redox-sensitive biomolecules (proteins) in the body. This will enable us to establish the broad application of our methods and substantially improve our ability to commercialize our discoveries.","institutions":["Monash University"],"researchers":["A\/Pr Lisandra Martin","Prof Raymond Rodgers"],"status":"CLOSED","fundingAmount":144500,"fundingScheme":"NHMRC Development Grants","startDate":2004,"endDate":2005,"dateTimeModified":"2017-07-11T08:28:19Z","dateTimeCreated":"2013-05-15T15:56:08Z","funder":["National Health and Medical Research Council"],"managingInstitution":["Monash University","Monash University","Monash University"],"principalInvestigator":["A\/Pr Lisandra Martin"],"purl":"https:\/\/purl.org\/au-research\/grants\/nhmrc\/284421","identifiers":["284421","https:\/\/purl.org\/au-research\/grants\/nhmrc\/284421"],"subjects":["270802","Biochemistry pharmacology","Biomaterials","Biosensor","Proteins chemistry","Recombinant proteins"],"links":[{"rel":"self","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants\/94547"}]}],"links":[{"rel":"grant","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/grants"},{"rel":"program","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/programs"},{"rel":"project","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/projects"},{"rel":"award","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/awards"},{"rel":"dataset","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/datasets"},{"rel":"funder","href":"http:\/\/researchdata.edu.au\/api\/v2.0\/registry\/activities\/funders"}]}}